Brainbow is a term used to describe a process by which individual neurons of a brain are mapped with fluorescent proteins, which allow the neurons to glow with specific colors under a light source. By controlling and varying the amount of red, green, and blue derivatives of green fluorescent protein expressed in individual neurons, it is possible to map each neuron with a distinctive color.
The technique was developed in the Spring of 2007 by a team led by Jeff W. Lichtman and Joshua R. Sanes, both professors of Molecular & Cellular Biology in the Department of Neurobiology at Harvard Medical School. While earlier techniques allowed for mapping only a few neurons, the new method allows more than 100 differently mapped neurons can be simultaneously mapped in this manner. The resulting images can be quite striking and have in fact won awards in science photography competitions.
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